VIP

This is a specialized research product of VIP, a naturally occurring neuropeptide, strictly intended For In Vitro Research Use Only — Not for Human or Veterinary Use.

Description & Application

• Description: Vasoactive Intestinal Peptide (VIP) is a synthetic 28-amino acid peptide that belongs to the glucagon/secretin superfamily. It acts as a potent hormone and neurotransmitter found in various tissues, including the gut, pancreas, and brain.

• Mechanism: VIP functions as a potent vasodilator and a key modulator of the immune system. It exerts its biological effects by binding to specific G protein-coupled receptors (VPAC1 and VPAC2), which triggers a cascade of intracellular signaling, primarily through the activation of adenylate cyclase.

• Research Focus: It is widely utilized in laboratory settings to investigate:

  • Anti-inflammatory pathways and the regulation of cytokine production.

  • Circadian rhythm modulation (VIP is critical for the synchronization of the SCN in the brain).

  • Vasodilation and blood flow regulation in respiratory and gastrointestinal models.

  • Neuroprotection and the modulation of the gut-brain axis.

  • Potential applications in research related to Chronic Inflammatory Response Syndrome (CIRS).

Specifications & Storage

• Unit Size: 5mg or 10mg per vial (check specific listing).

• Form: Lyophilized (freeze-dried) powder.

• Sequence: $\text{His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn}$

• Molecular Weight: ~3325.8 Da.

• Storage (Dry): Store in a cool, dry environment (preferably $-20^{\circ}\text{C}$ for long-term stability).

• Storage (Reconstituted): After reconstitution with sterile or bacteriostatic water, the solution must be refrigerated at $2^{\circ}\text{C}–8^{\circ}\text{C}$.

⚠️ Legal & Intended Use

• Intended Use: This compound is intended strictly for qualified in vitro laboratory research. It is not approved for human or animal use and must not be used in food, drugs, supplements, or cosmetics.

• Legal Disclaimer: This product and associated statements have not been evaluated by the FDA. No claims are made regarding the diagnosis, treatment, cure, or prevention of any disease. Use is restricted to certified laboratories and research institutions.

• Terms of Sale: All sales are final. By purchasing from Mile High Compounds, the buyer affirms they are a qualified researcher and assumes full responsibility for proper handling and regulatory compliance.