Tesofensine

This is a specialized research product of Tesofensine (NS-2330), a potent triple monoamine reuptake inhibitor (SNDRI), strictly intended For In Vitro Research Use Only — Not for Human or Veterinary Use.1

Description & Application

• Description: Tesofensine is a unique compound from the phenyltropane family.2 It acts as a triple reuptake inhibitor, effectively increasing the synaptic availability of Dopamine, Serotonin, and Noradrenaline.3

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• Mechanism: By modulating these three critical neurotransmitters, Tesofensine is researched for its potent effects on appetite regulation, food-seeking behavior, and metabolic rate.4 Unlike standard stimulants, it is noted for a significantly longer half-life (approx.5 9 days) and a distinct pharmacological profile.

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• Research Focus: It is primarily utilized in laboratory settings to investigate:

  • Appetite suppression via lateral hypothalamus modulation.6

  • Energy expenditure and resting metabolic rate increases.7

  • Inhibition of GABAergic neurons involved in feeding.

  • Cognitive enhancement and neuroprotective signaling (BDNF elevation).8

  • Weight loss maintenance and the prevention of "rebound" weight gain.9

Specifications & Storage

• Form: Available in Tablet or Powder format (refer to specific Mile High Compounds listing for current unit size).

• Molecular Formula: 10$C_{17}H_{23}Cl_{2}NO$.11

• Molecular Weight: ~328.28 g/mol.12

• Storage (Dry): Store in a cool, dry environment ($2^{\circ}\text{C}–8^{\circ}\text{C}$) protected from light.

• Storage (Long-term): For extended stability, store at -20°C.13

• Solubility: Soluble in DMSO, Ethanol, and Methanol.

⚠️ Legal & Intended Use

• Intended Use: This compound is intended strictly for qualified in vitro laboratory research.14 It is not approved for human or animal consumption and must not be used in food, drugs, supplements, or cosmetics.15

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• Legal Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Use is restricted to certified laboratories and research institutions.

• Terms of Sale: All sales are final. By purchasing from Mile High Compounds, the buyer affirms they are a qualified researcher and assumes full responsibility for proper handling, storage, and regulatory compliance.