LL-37 (Cathelicidin)
$49.99$34.99
This is a specialized research product of LL-37, a multifaceted antimicrobial peptide (AMP), strictly intended For In Vitro Research Use Only — Not for Human or Veterinary Use.
Description & Application
Description: LL-37 is a 37-amino acid peptide and the only member of the cathelicidin family found in humans. It is naturally produced by various cells, including neutrophils and epithelial cells, as part of the innate immune response.
Mechanism: In research models, LL-37 is known for its broad-spectrum antimicrobial activity. It functions by disrupting the cell membranes of bacteria, fungi, and certain viruses. Beyond direct antimicrobial action, it acts as a signaling molecule that can modulate inflammatory responses and promote wound healing.
Research Focus: It is widely utilized in laboratory settings to investigate:
Innate immunity and host-defense mechanisms.
Angiogenesis and tissue regeneration pathways.
Biofilm disruption and antimicrobial resistance models.
Modulation of inflammatory cytokines and chemotaxis of immune cells.
Potential roles in autoimmune signaling and tumor microenvironment research.
Specifications & Storage
Unit Size: 5mg or 10mg per vial (check specific listing).
Form: Lyophilized (freeze-dried) powder.
Sequence: $\text{Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser}$
Molecular Weight: ~4493.3 Da.
Storage (Dry): Store in a cool, dry environment (preferably $-20^{\circ}\text{C}$ for long-term stability).
Storage (Reconstituted): After reconstitution with sterile or bacteriostatic water, the solution must be refrigerated at $2^{\circ}\text{C}–8^{\circ}\text{C}$.
⚠️ Legal & Intended Use
Intended Use: This compound is intended strictly for qualified in vitro laboratory research. It is not approved for human or animal use and must not be used in food, drugs, supplements, or cosmetics.
Legal Disclaimer: This product and associated statements have not been evaluated by the FDA. No claims are made regarding the diagnosis, treatment, cure, or prevention of any disease. Use is restricted to certified laboratories and research institutions.
Terms of Sale: All sales are final. By purchasing from Mile High Compounds, the buyer affirms they are a qualified researcher and assumes full responsibility for proper handling and regulatory compliance.