Kisspeptin-10 (10mg)
$63.00$34.99
This is a specialized research product of Kisspeptin-10 from Core Peptides, a naturally occurring peptide encoded by the KISS1 gene, strictly intended For Research and Laboratory Purposes Only — Not for Human Consumption.
Description & Application
Description: Kisspeptin-10 (also known as Kisspeptin 45-54) is a truncated, biologically active decapeptide fragment of the larger 145-amino acid Kisspeptin protein.
Mechanism: It acts as a primary ligand for the G-protein coupled receptor 54 (GPR54), also known as the KISS1 receptor. By binding to this receptor, Kisspeptin-10 is a critical regulator of the Hypothalamic-Pituitary-Gonadal (HPG) axis, stimulating the release of Gonadotropin-Releasing Hormone (GnRH), which in turn triggers the release of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).
Research Focus: In laboratory settings, it is investigated for:
Reproductive Biology: Its role in puberty onset, fertility regulation, and potential in research models of hypogonadotropic hypogonadism and PCOS.
Metastasis Suppression: Its origin as a suppressor of melanoma and breast cancer cell migration.
Neuroprotection: Potential to mitigate the toxicity induced by amyloid-beta ($A\beta$) and alpha-synuclein ($\alpha$-syn) in cholinergic neurons, potentially through GPR54-independent pathways.
Metabolic Regulation: Impact on food intake, appetite control, and glucose tolerance.
Emotional/Limbic Activity: Effects on brain processing related to bonding and sexual stimuli.
Specifications & Storage
Unit Size: 10mg (provided as a lyophilized powder).
Purity: >99% (verified via HPLC and Mass Spectrometry).
Molecular Formula: $C_{63}H_{83}N_{17}O_{14}$.
Molecular Weight: 1302.4 g/mol.
Other Names: Kisspeptin 45-54.
Storage: Store in a cool, dry place. For long-term preservation of research integrity, refrigeration ($2^{\circ}\text{C}–8^{\circ}\text{C}$) or freezing ($-20^{\circ}\text{C}$) is recommended for the lyophilized powder.
⚠️ Legal & Intended Use
Intended Use: This compound is intended strictly for research and laboratory purposes. It is not approved for human or animal consumption and must not be used in food, drugs, supplements, or cosmetics.
Legal Disclaimer: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Compliance: Core Peptides is a chemical supplier and not a compounding pharmacy. Use is restricted to qualified research professionals in controlled laboratory environments.
Safety: Misuse of this product for human or animal use is strictly prohibited.